Amherst College, Amherst, MA, B.A., 1980, Chemistry
Ohio State University College of Medicine, Columbus, Ohio, M.D., 1984, Medicine

Francis Scott Key Medical Center, Baltimore, MD. Internship: Medicine/Psychiatry, 1984-1985.

Johns Hopkins Hospital, Baltimore, MD. Residency: Psychiatry, 1985-1988.

Johns Hopkins Hospital, Baltimore, MD. Chief Resident, Psychiatry, 1987-1988.

Behavioral Pharmacology Research Unit, Johns Hopkins School of Medicine, Baltimore, MD. Post Doctoral Fellowship, 1988-1990.

Johns Hopkins School of Medicine, Baltimore, MD. Assistant Professor, Department of Psychiatry and Behavioral Sciences, 1990-1994.

Johns Hopkins School of Medicine, Baltimore, MD. Associate Professor, Department of Psychiatry and Behavioral Sciences, 1995-present.

Member, Drug Abuse Advisory Committee of the Food and Drug Administration: 1996 -- 2000 (Chairman, 1997 -- 2000)

Member, Data Monitoring Board, National Institute on Drug Abuse/Department of Veterans Affairs Cooperative Studies Program: 1997

Pearlson G., Strain E.C. Chronic pain and depression. In: Robinson R.G., and Rabins P.V. (Eds.) Depression in Medical Illness. New York: Igaku-Shoin, 1989.

Brooner R.K., Bigelow G.E., Strain E.C., Schmidt C.W. Intravenous drug abusers with antisocial personality disorder: Increased HIV risk behavior. Drug Alcohol Depend, 1990, 26:39-44.

Preston K.L., Bigelow G.E., Casani J.A., Strain E.C. Intravenous cocaine: Subjective and physiologic effects and desire for cocaine. Clin Pharmacol Ther, 1990, 47:168.

Strain E.C., Stitzer M.L., Bigelow G.E. The early treatment time course of depressive symptoms in opiate addicts. J Nerv Mental Dis, 1991, 179:215-221.

Strain E.C., Brooner R.K., Bigelow G.E. Clustering of multiple substance use and psychiatric diagnoses in opiate addicts. Drug Alcohol Depend, 1991, 27:127-134.

Strain E.C., Bigelow G.E., Preston K.L., Liebson I. Limited abuse liability of buprenorphine in methadone-dependent volunteers. Clin Pharmacol Ther, 1991, 49:167.

Strain E.C., Preston K.L., Liebson I.A., Bigelow G.E. Acute effects of buprenorphine, hydromorphone, and naloxone in methadone-dependent volunteers. J Pharmacol Exp Ther, 1992, 261:985-993.

Silverman K., Evans S.M., Strain E.C., Griffiths R.R. Withdrawal syndrome after double-blind cessation of caffeine consumption. N Engl J Med, 1992, 327:1109-1114.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Methadone dose and treatment outcome. Drug Alcohol Depend, 1993, 33:105-117.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Dose-response effects of methadone in the treatment of opioid dependence. Ann Int Med, 1993, 119:23-27.

Strain E.C., Buccino D.L., Brooner R.K., Schmidt C.W., Bigelow G.E. The triply diagnosed: Patients with major mental illness, cognitive impairment, and substance abuse.. J Nerv Mental Dis, 1993, 181:585-587.

Strain E.C., Preston K.L., Liebson I.A., Bigelow G.E. Precipitated withdrawal by pentazocine in methadone-maintained volunteers. J Pharmacol Exp Ther, 1993, 267:624-634.

Strain E.C., Preston K.L., Stitzer M.L., Liebson I.A., Bigelow G.E. The effects of cocaine in buprenorphine-maintained outpatient volunteers: Results from clinical experience and laboratory challenges. Am J Addictions, 1994, 3:129-143.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Comparison of buprenorphine and methadone in the treatment of opioid dependence. Am J Psychiatry, 1994, 151:1025-1030.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Outcome after methadone treatment: Influence of prior treatment factors and current treatment status. Drug Alcohol Depend, 1994, 35:223-230.

Strain E.C., Mumford G.K., Silverman K., Griffiths R.R. Caffeine dependence syndrome: Evidence from case histories and experimental evaluations. JAMA, 1994, 272:1043-1048.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Buprenorphine versus methadone in the treatment of opioid dependent cocaine users. Psychopharmacol, 1994, 116:401-406.

Strain E.C. Antisocial personality disorder, misbehavior and drug abuse (commentary). J Nerv Ment Dis, 1995, 183:162-165.

Strain E.C., Preston K.L. Liebson I.A., Bigelow G.E. Buprenorphine effects in methadone-maintained volunteers: Effects at two hours after methadone. J Pharmacol Exp Ther, 1995, 272:628-638.

Strain E.C., Griffiths R.R. Caffeine dependence: Fact or fiction? (commentary) J Royal Soc Med, 1995, 88:437-440.

Johnson R.E., Eissenberg T., Stitzer M.L., Strain E.C., Liebson I.A., Bigelow G.E. A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence. Drug Alcohol Depend, 1995, 40:17-25.

Johnson R.E., Eissenberg T., Stitzer M.L., Strain E.C., Liebson I.A., Bigelow G.E. Buprenorphine treatment of opioid dependence: Clinical trial of daily versus alternate-day dosing. Drug Alcohol Depend, 1995, 40:27-35.

Preston K.L., Sullivan J.T., Strain E.C., Bigelow G.E. Enhancement of cocaine's abuse liability in methadone-maintenance patients. Psychopharmacol, 1996, 123:15-25.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Buprenorphine versus methadone in the treatment of opioid dependence: Self-reports, urinalysis and Addiction Severity Index. J Clin Psychopharmacol, 1996, 6:58-67.

Strain E.C., Griffiths R.R. Caffeine dependence: Fact or fiction? Woman’s Health Digest 1996, 2:15-17. (Reprinted from J Royal Soc Med. 88:437-440)

Strain E.C., Griffiths R.R. Caffeine use disorders. In: Tasman A., Kay J., Lieberman J.A. (Eds.) Psychiatry. Philadelphia: W.B. Saunders, 1997.

Strain E.C., Griffiths R.R. Caffeine use disorders. In: Taylor D.H., Tasman A. (Eds.) Psychiatry: Self-Assessment and Review. Philadelphia: W.B. Saunders, 1997.

Strain E.C., Preston K.L. Liebson I.A., Bigelow G.E. Opioid antagonist effects of dezocine in opioid-dependent humans. Clin Pharmacol Ther, 1996, 60:206-217.

Strain E.C., Walsh S.L., Preston K.L., Liebson I.A., Bigelow G.E. The effects of buprenorphine in buprenorphine-maintained volunteers. Psychopharmacol, 1997, 129:329-338.

Eissenberg T., Bigelow G.E., Strain E.C., Walsh S.L., Brooner R.K., Stitzer M.L., Johnson R.E. Dose-related efficacy of levo-alpha acetyl methadol for treatment of opioid dependence: A randomized clinical trial. JAMA, 1997, 277:1945-1951.

Schlaepfer T.E., Strain E.C., Greenberg B.D., Preston K.L., Lancaster E., Bigelow G.E., Barta P.E., Pearlson G.D. Site of opioid action in the human brain: mu and kappa agonists produce different subjective and cerebral blood flow effects. Am J Psychiatry, 1998, 155:470-473.

Jones H.E., Strain E.C., Bigelow G.E., Walsh S.L., Stitzer M.L., Eissenberg T., Johnson R.E. Induction onto LAAM: safety and efficacy. Arch Gen Psychiatry, 1998, 55:729-736.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Useful predictors of outcome in methadone-treated patients. J Maint Addict, 1998, 1:15-28.

Strain E.C., Stitzer M.L., Liebson I.A., Bigelow G.E. Randomized controlled trial of moderate versus high dose methadone in treatment of opioid dependence. JAMA, 1999, 281:1000-1005.

Strain E.C. Rethinking lessons learned. (commentary on "Psychosocial treatments for cocaine dependence: results of the National Institute on Drug Abuse Collaborative Cocaine Treatment study" by Crits-Christoph et al.) Arch Gen Psychiatry, 1999, 56:503-504.

E-mail contact: ecsgss@aol.com